Overexpression of lpxT Gene in Escherichia coli Inhibits Cell Division and Causes Envelope Defects without Changing the Overall Phosphorylation Level of Lipid A
LpxT is an inner membrane protein that transfers a phosphate group from the essential lipid undecaprenyl pyrophosphate (C-55PP) to the lipid A moiety f1400ea-sb34 of lipopolysaccharide, generating a lipid A tris-phosphorylated species.The protein is encoded by the non-essential lpxT gene, which is conserved in distantly related Gram-negative bacter